Then again, the great news is there are many means to mend the damage and in a few cases limit the complication of the disease. A few of the most typical causes are certain medications, heredity, connective tissue disorders, vasculitis, and trauma to an individual’s penis.

Below are the things are currently known about the different causes of the condition:


There are a few medications that can perhaps bring about such a condition. The majority of these drugs are heart or blood pressure medications that make use of beta-blockers. Then again, there is even an optical or eye medication utilized to treat glaucoma that has beta-blockers as well. Several drugs that deal with seizure and multiple sclerosis might bring about this disease too. The chances of medications causing such condition are rather low and any sufferer that is presently on medication ought to check with his physician before discounting the drug he is taking.


The said condition could run in families, signifying there is a hereditary link in the cause of Peyronie’s syndrome.

Connective tissue diseases

Examples of connective tissues are bones, cartilage, and an individual’s skin. Roughly thirty percent who have this condition as well as contracts connective tissue diseases in other regions of their bodies. Such an association can be related to an auto-immunologic disorder.


Vasculitis is the irritation and swelling of a person’s blood vessels. Inflammation could over time result in scar tissues that bring about Peyronie’s syndrome. Because of the slow accumulation of the scar tissues, it might be tough to initially detect the signs and symptoms of the condition. Vasculitis could as well result in long term penile curvature that usually requires treatment.

Penile trauma

Trauma itself isn’t the cause though the plaque that accumulates in the wound healing process is an identified cause. Typically, this is from bending or bumping the penis in sexual intercourse which results in a little internal bleeding. With penile trauma, the condition could develop somewhat quickly, but in the majority of these cases, it could as well disappear without having any treatment. As the wound mends in due course, the plaque deposits naturally dissolve.

The positive news

Universities and government agencies are still researching and studying the different causes and treatments of Peyronie’s syndrome. At present, various treatments are on hand ranging from oral supplements like vitamin E and other medications, making use of penile traction devices to fix the curvature of a person’s penis, injections into the organ, and ultimately, penile surgery.

For people who are suffering from the said condition, it is only prudent to consult your doctor so that he could help you treat the underlying disease if there are any. Or, in regards, a cause such as medications, a physician can perhaps change your drug regimen.

And for individuals who want to avoid developing Peyronie’s syndrome, keep in mind the cited causes like being more careful when having intercourse with your partner.

Study and research base

Peyronie’s Disease (Penile Curvature): Symptoms, Causes, Treatments

Peyronie’s disease – Symptoms and causes – Mayo Clinic

What is Peyronie’s Disease? – Urology Care Foundation

Penile Curvature (Peyronie’s Disease) | NIDDK

The curvature of the Penis (Peyronie’s Disease) – Harvard Health

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